Pastel BioScience has developed highly sophisticated bioinformatics to identify the motifs within proteins and therefore the resulting "fingerprints" that will uniquely identify virtually all proteins. A major advantage is that by uing this concept of motif recognition Pastel's InVenio™ biomarker discovery & validation platform will be applicable across the proteomes of all organisms, unlike antibody array technologies that are organism specific.


Pastel has also optimised the multiplexing capabilities of its capture molecules for the identification of all of the proteins of the human proteome.

Pastel's scientists have gone on to show that by using a minimal number of highly multiplexed recognition motifs, less than 8,000, it is possible to uniquely identify in excess of 100,000 proteins from human, mouse, nematode, bacterial and viral proteomes. More recent work has shown the applicability of this technology to the identification of splice variants (isoforms), single amino acid variants, and post-translational modifications.

Moreover, a high-resolution dataset has also been optimised which, having a high level of redundancy, will allow the potential identification of previously unidentified proteins and protein variants making this technology applicable to novel human protein identification, novel pathogen identification and biowarfare surveillance.