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Glossary The following terms may be useful for your understanding of Pastel BioScience's technologies and the markets in which it operates. Affinity The "tightness" with which a capture molecule binds to its target. A molecule having high affinity for its target will remain bound even under stringent washing conditions whereas lower affinity molecules will be detached and removed. Bioinformatics The process of examining 'mining' test results, using a range of statistical techniques and pattern recognition algorithms, from large numbers of samples to find potentially useful information. Capture Molecule A capture molecule normally recognises, in a specific manner, a target molecule through interactions between the two based most commonly on the three-dimensional surface structure of the target molecule. Capture molecules are most generally antibodies and their derivatives but can also be other protein based scaffolds - fibronectin, MHC receptors or even non-protein based entities such as DNA in the case of aptamers or plastic like polymers in the case of molecular imprinting. |
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