Previously unidentified organisms
The appearance of the previously unidentified SARS virus in 2002, the current concerns of pathogenic strains of the Avian flu virus and even the identification of HIV as the causative agent of AIDS back in 1985 highlight the fact that there is still a lack of understanding as to the numbers, nature, epidimiology and identification of emerging and undiscovered pathogenic organisms. While those that are of major concern are pathogenic for humans the identification of agents which may devastate commercially sensitive livestock or arable crops should be of equal importance.
There are many technologies available that are able to quickly identify with good sensitivity and specificity known organisms and their derived markers, usually proteins or DNA. There are however, very few technologies or assays that are able to identify markers which have not been previously identified.
Pastel has, through its bioinformatics, shown that if InVenio™ Technology had been available in 2002 it would have been able to detect at least one of the SARS proteins through a unique signature or fingerprint not found in any other human protein. Pastel has also extended this by creating random protein sequences, almost all of which would be identifiable with InVenio™ Technology.
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